Additionally drought, unused management methods in applied of water resource in agriculture lead to shortage of water in different subjects such as farm and garden management. One of the solutions water source management about shortage water problem in agriculture is applied urban wastewater. This research was conducted to investigate the effect of urban wastewater management and water deficit method on the yield and physiological characteristics of millet. Therefore, a Completely randomized block design with split plot arrangement with Irrigation source is at three levels (I1 and I2 and I3: wastewater, the well and the well-wastewater alternate respectively, irrigation at three levels (C1, C2 and C3: irrigation with 100%, 50% and 30%water requirement respectively), with three replications at the research farm of the water and sewage company of Birjand. The result of this research was indicated that using of urban wastewater as irrigation source had significant effect on physiological characteristics of millet such as plant performance, 1000 seed weight and water use efficiency. The plant height value in alternative treat with the best yield to test treat was indicated 20% increasing of variation of course under deficit irrigation in 30 level percent demand water was observed 5 % decreasing of variation. The weight of each cluster (gr) in wastewater treat to test treat had 18 % increasing of variation. Also, under deficit irrigation, the water use efficiency of the well-wastewater alternate to test had increased to 5 at the 50 and 30 level percent demand water. The obtained results represent the effective role of urban wastewater with the well on growth of the plant millet grass that lead to improve physiological characteristics and also increase yield of millet. So, use of urban wastewater is a valuable to Management of water resources in agriculture.