Optimal water resource management is one of the most critical strategies for achieving sustainable and efficient water consumption worldwide. The proper design and implementation of irrigation channels play a key role in this regard. This study investigates the impact of initial soil moisture, channel bed width, and channel side slope on the cumulative water infiltration in farm irrigation channels. Experiments were conducted in 12 standardized test channels with a length of 1 meter, a depth of 30 cm, and variable widths. The experimental treatments included three levels of initial soil moisture (3%, 6%, and 50%), two channel bed widths (10 cm and 20 cm), and two channel side slopes (less than 1% and more than 3%). The soil texture was kept constant as loamy-clay in all experiments, and cumulative water infiltration was analyzed through field measurements. The analysis of variance (ANOVA) results indicated that the effects of the studied parameters on cumulative infiltration were statistically significant at the 99% confidence level (p-value < 0.01). Treatments with lower initial soil moisture (3% and 6%) recorded cumulative infiltration averages of 24 cm and 29 cm, respectively, whereas this value decreased to 15.6 cm for treatments with 50% initial soil moisture. Moreover, increasing the channel bed width from 10 cm to 20 cm led to an increase in cumulative infiltration from 15 cm to 21.3 cm.